Management of thyroid cancer associated with elevated serum thyroglobulin and negative radioiodine scanning
نویسندگان
چکیده
Aim: Differentiated thyroid carcinoma has a favorable prognosis, even in the presence of distant metastases, if the tumor cells are able to concentrate radioiodine. Nonetheless, up to 30% of thyroid cancer patients with elevated serum thyroglobulin (Tg) and negative radioiodine whole-body scan findings represent a diagnostic dilemma. In this study we assessed the diagnostic contribution of anatomical and functional imaging procedures, including US of the thyroid bed and neck, CT scanning of the chest and mediastinum, and FDG PET whole-body scanning, in iodine-negative/Tg-positive thyroid cancer patients.
منابع مشابه
Differentiated Thyroid Carcinoma with Elevated Thyroglobulin and Negative Radioiodine Whole-Body Scan Metastases
Serum thyroglobulin (Tg) and Tg antibody (TgAb) levels, together with neck ultrasonography and 131I whole-body scintigraphy (WBS), are diagnostic tools for postoperative follow-up of patients with differentiated thyroid carcinoma (DTC). Generally, good correlation is seen between Tg and WBS in follow-up studies for DTC after thyroid remnant ablation. Undetectable serum Tg with negative WBS resu...
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